Avascular Necrosis Shoulder

Medical research has identified a number of risk factors associated with AVN.

Interestingly, not everyone who has a risk factor gets AVN and not everyone with AVN has an easily identifiable risk factor, meaning the cause is unknown or idiopathic.

People who have a fracture of the proximal humerus (ball part of the shoulder) are at risk for AVN.

With a fracture of the proximal humerus the blood supply can be disrupted and loss of the normal blood flow to the bone may cause it to eventually die and become necrotic.

The more extensive the fracture the more likely is this development of AVN.

Another common cause of AVN is the effect of steroids given for other conditions.

The steroids are believed to damage the health of the cells which make bone in the humeral head and when they die the sequence of AVN occurs.

Other causes of AVN can be radiation or chemotherapy treatment in the case of cancer.

Other rare causes include sickle cell disease, Gaucher’s disease, Caisson’s disease (also known as diver’s disease or the bends:

This is due to sudden change in water pressure in deep sea diving where nitrogen bubbles form in the blood and damage the blood supply to the humeral head). 

AVN Avascular Necrosis aka Osteonecrosis ON

usually presents as pain and may also be associated with noise and crunching sensation (crepitation) in the shoulder with movement.

Movement may be limited due to pain. About 50% of individuals who develop atraumatic (without a fracture) AVN in the shoulder will also have involvement of other joints.

In its early stages AVN may not be apparent on a plain x-ray but it can be seen on an MRI (described above).

As it progresses with collapse of the humeral head and eventual arthritis it is clearly seen on an x-ray (see figures below).

4(1)

Stage 1 is a shoulder with a normal X-ray but signal changes on MRI showing subchondral edema.

Stage 2 is a shoulder with more whitened bone called sclerosis, near the joint surface (subchondral).

Stage 3 demonstrates a crescent sign or collapse or fracture of the subchondral bone.

Stage 4 demonstrates flattening of the humeral head from advanced collapse.

Stage 5 or end-stage AVN demonstrates advanced collapse of the humerus with degenerative changes of the glenoid (arthritis).

A study that looked at 200 shoulders with AVN found that about 40% of shoulders with early AVN progressed in 3 years to advanced AVN.

Patients that presented with later-stage AVN, 55-80% of patients (depending on how late the stage) progressed to advanced AVN6.

Drilling of the humeral head, called core decompression, is a treatment which may be helpful in the early stages of AVN before the humeral head collapses.

It is believed that pressure in the bone goes up when the blood supply is lost and that pain can be relieved by decompressing the bone by drilling into it.

This is called core decompression. This may also stimulate better blood supply and faster healing in the humeral head.

Facts

• A condition caused by interruption of blood supply to humeral head

• Pathophysiology

◦ pathoanatomy 

decreased blood supply to humeral head leading to death of cells in bony matrix.

bone is resorbed and remodeled, causing subchondral bone collapse and may lead to joint incongruity and arthritic changes

◦ etiology similar to hip

Remember ASEPTIC mneumonic 

Alcohol, AIDS

Steroids (most common), Sickle, SLE

Erlenmeyer flask (Gaucher’s)

Pancreatitis

Trauma

Idiopathic/ Infection

Caisson’s (the bends)

may be atraumatic

posttraumatic

four-part fracture-dislocations approach 100% AVN

displaced four-part fractures ~45% AVN

valgus impacted four-part ~11% AVN

three-part ~14% AVN

• Prognosis

◦ related to stage of disease

Anatomy

• Blood supply

◦ Humeral head

ascending branch of anterior humeral circumflex artery and arcuate artery

provides blood supply to humeral head

vessel runs parallel to lateral aspect of tendon of long head of biceps in the bicipital groove

beware not to injure when plating proximal humerus fractures

arcuate artery is the interosseous continuation of ascending branch of anterior humeral circumflex artery and penetrates the bone of the humeral head

provides 35% of blood supply to humeral head

posterior humeral circumflex artery

most current literature supports this as providing the main blood supply to humeral head 

provides 65% of blood supply 

Classification

 

Cruess Classification (stages)

Stage I

Normal x-ray. Changes on MRI. Core decompression.

Stage II

Sclerosis (wedged, mottled), osteopenia. Core decompression.

Stage III

Crescent sign indicating a subchondral fracture. Resurfacing or hemiarthroplasty.

Stage IV

Flattening and collapse. Resurfacing or hemiarthroplasty.

Stage V

Degenerative changes extend to glenoid. TSA.

 

 

Presentation

• Symptoms

◦ insidious onset of shoulder pain

often without a clear inciting event

◦ pain, loss of motion, crepitus, and weakness

• Physical exam

◦ limited range of motion

◦ crepitus

◦ weakness of the rotator cuff and deltoid muscles

Imaging

• Radiographs

◦ recommended views

five views of shoulder (shown best in neutral rotation AP)

◦ findings

no findings on radiograph at onset of disease process

osteolytic lesion develops on radiograph demonstrating resorption of subchondral necrosis

most common initial site is superior middle portion of humeral head

crescent sign demonstrates subchondral collapse

may progress to depression of articular surface and consequent arthritic changes.

• MRI

◦ preferred imaging modality

~100% sensitivity in detection

◦ will demonstrate edema at the site of subchondral sclerosis 

Treatment

• Nonoperative

◦ pain medications, activity modification, physical therapy

indications

first line of treatment

technique

physical therapy

restrict overhead activity and manual labor

• Operative

◦ core decompression + arthroscopy (confirm integrity of cartilage)  

indications

early disease (precollapse Cruess Stage I and II)

◦ humeral head resurfacing

indications

Stage III disease with focal chondral defects, and sufficient remaining epiphyseal bone stock for fixation.

◦ hemiarthroplasty  

indications

moderate disease (Cruess Stage III and IV)

◦ total shoulder arthroplasty 

indications

advance stage (Cruess V)

References

  1. Mont MA, Payman RK, Laporte DM, Petri M, Jones LC, Hungerford DS: Atraumatic osteonecrosis of the humeral head. J Rheumatol 2000; 27:1766-1773
  2. Hasan S, Romeo A: Nontraumatic osteonecrosis of the humeral head J Shoulder Elbow Surg 2008; 281-298
  3. CruessRL: Corticosteroid-induced osteonecrosis of the humeralhead. Orthop Clin North Am 1985; 16:789-796.
  4. LaPorteDM, MontMA, MohanV, JonesLC, HungerfordDS: Multifocal osteonecrosis. J Rheumatol 1998; 25:1968-1974.
  5. CruessRL: Experience with steroid-induced avascular necrosis of the shoulder and etiologic considerations regarding osteonecrosis of the hip. Clin Orthop Relat Res 1978; 130:86-93
  6. HattrupSJ, CofieldRH Osteonecrosis of the humeral head: Relationship of disease stage, extent, and cause to natural history. J Shoulder Elbow Surg 1999; 8:559-564.
  7. Feeley BT, Fealy S, Dines DM, Warren RF, Craig EV. Hemiarthroplasty and total shoulder arthroplasty for avascular necrosis of the humeral head. J Shoulder Elbow Surg 2008;17(5): 689-694.
  8. Harreld KL, Marker DR, Wiesler ER, Shafiq B, Mont M. Osteonecrosis of the Humeral Head. J Am Academy of Orthop Surgeons 2009;17(6): 345-355.

Published by

ChronicallyGratefulDebla

The body always knows what to do to heal itself. The challenge is listening and doing what your body needs. I was diagnosed with Osteoarthritis in 2012, Avascular Necrosis aka Osteonecrosis in 2014 and Factor V Leiden hetero, Spondylolisthesis 2016 Health Advocate for all above and more Health Activist World Changer Love photography, cooking, hiking,walking and learning to live a new normal since my diagnosis. And also Advocate for Heart Disease it's something I learned about as a kid ,both parents had it and now so does my husband. My Links Support Group Avascular Necrosis/Osteonecrosis Support Int’l https://m.facebook.com/groups/DeadBoneDiseaseAvn Facebook Main Profile https://m.facebook.com/public/Deborah-Andio Main Blog ChronicallyGratefulDebla.com YouTube Awareness Videos https://m.youtube.com/user/debbieandio New Blog on Google 3/8/2017 http://chronicallygratefuldebla.blogspot.com/2017/03/hello-i-am-debbie-andio-i-am-blogger.html Link to Mini Fact Videos http://cortanavideo.trade/user/UC1RtmEwtWKC8w9EgE2IwOFg Twitter https://mobile.twitter.com/debbiea001 Instagram https://www.instagram.com/debbiea_1962 FB Information and Awareness Pages Bone info and Joint of the Day https://m.facebook.com/AvascularNecrosisRareDiseaseDayFeb29/ ON/AVN https://m.facebook.com/Osteonecrosis-Avascular-Necrosis-Support-913679995417381/ ON/AVN https://m.facebook.com/ONAvascular-Necrosis-Knowledge-752404224891578/ Recipes https://m.facebook.com/YummyGoodness/ Facebook Link https://m.facebook.com/ChronicallyGrateful.Me/ New Morning Talk Anyone who wants to do a f b live via a guest message me. Various topics health, pain, food https://m.facebook.com/MorningTalk.Health/

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