Osteonecrosis and Organ transplant

Osteonecrosis is a well-recognized complication associated with organ transplantation.

It is a pathological condition characterized by the death of the cellular constituents of bone and marrow. The process of aseptic bone necrosis is associated with glucocorticoid use, and the mechanism by which glucocorticoids initiate the pathologic process has recently been elucidated.

Rates are particularly high in patients with systemic lupus erythematosus. The incidence of osteonecrosis also increases in patients on dialysis.

The exact prevalence of osteonecrosis after organ transplantation is, however, difficult to assess as many cases are clinically silent.

The most common symptom of osteonecrosis is hip pain that is usually deep in nature, localized to the groin with occasional radiation down the thigh to the knee.

Symptoms are usually exacerbated by physical activity and weight bearing and relieved by rest. In the late stages of osteonecrosis, pain is often present at rest, and patients may develop a limp, as they are no longer able to bear weight on the affected joint.

Osteonecrosis affecting the bone beneath a weight-bearing joint surface is associated with a significant risk of developing a subarticular fracture, which appears to initiate the symptoms.

Optimizing the dose of glucocorticoids has led to a significant reduction in the incidence of osteonecrosis post-transplantation. Substituting these agents entirely with calcineurin inhibitors may decrease this complication of the transplantation process even further. Early diagnosis using magnetic resonance imaging is essential for the success of available surgical interventions

Reference: https://www.sciencedirect.com/science/article/pii/B9780121835026500213

https://online.boneandjoint.org.uk/doi/full/10.1302/0301-620x.89b12.19400?journalCode=bjj&

http://www0.sun.ac.za/aotc/general/renal/renal.php

Out with the old and in with the new

Being an advocate for bone and joint pain and personally living with osteoarthritis osteonecrosis and spondylolisthesis pain .

I saw our community struggle in new and ways besides living and dealing with daily pain.

People suddenly couldn’t access routine care because of lockdowns, fear and added anxiety.

They became more isolated than ever before. They and their family members faced job losses and financial hardship.

As an advocate for arthritis and a facilitator for my local LIVE YES Connect Group, I had to cancel or postpone in-person programs and events.

But on the plus side we went virtual on Zoom

Some members and their families faced added strain, whether dealing with virtual school or safety concerns for loved ones in nursing homes.

It’s a year most are happy to see come to an end.

But as a person with pain, I am always compelled to find silver linings. Even in the mist of challenging of times.

In 2020, I got to travel to Washington D.C participate in a focus group and then speak on Capital Hill.

I met some fantastic people from our state representatives to other leaders and advocates who work so hard to create a strong support system for so many causes and conditions.

I got to stay in a great city and tour the beautiful historical city of Washington D.C

We made great strides in accessibility, as health care system finally embraced telehealth and more companies allowed remote work.

Many disabled now gave hope to possibly getting a part time job working from home now because we see it is doable.

We seen a President work tirelessly to get pharmaceutical companies to create a vaccine quickly that will be safe for the USA and world.

We gave witnessed the power of science and innovation with the development of promising treatments and vaccines.

We saw our neighbors and communities come together to support one another in their time of need.

Despite the news only showing negativity there was a lot of positive happening.

2020 shown how resilient we are. And to never lose faith. Be grateful for everyday.

I don’t know what 2021 will bring;

I’m hoping it will be a fantastic year.

I just want to Thank you for your support, and following me on IG, Blog, and all social media platforms I promise to bring you current and uplifting information in 2021 and I wish you all a safe, healthy, prosperous and happy new year

Awareness Day For Avascular Necrosis- Osteonecrosis

Several states have officially proclaimed today as Osteonecrosis awareness day this past year a few more states came on the awareness train. And by next year God willing all 50 state’s as well as the US Virgin Islands and Puerto Rico will as well.

I will post the entire list later

But for now – Below are some posts and info

https://avascularnecrosiseducation.com/2020/05/24/avascular-necrosis-mask/amp/

Today is Avascular Necrosis Osteonecrosis Awareness Day

https://avascularnecrosiseducation.com/tag/educate/

https://avascularnecrosiseducation.com/2019/11/18/official-proclamation-avascular-necrosis-osteonecrosis-awareness-dsy-november-29/

Thank You Arizona

The good news keeps rolling in

Rare Disease Day is February 29 usually 28 on non leap years.

So as you know I have been working very hard on November 29 being National – Avascular Necrosis Osteonecrosis awareness day and all states have come on board so far but still waiting to hear from maybe 10 states.

They are doing all they can. And I am so pleased many states have issues proclamations for November 29 and many still are in the process.

Today The State of Arizona sent a proclamation for rare disease awareness we got the entire week February 20-27

And they will also be recognizing November 29

So blessed.

Hard work pays off

Thank you State of Arizona

Deb Andio

Founder Avascular Necrosis Osteonecrosis Support Int’l

#Osteonecrisis #AvascularNecrosis

Radionuclide bone scan to diagnose or confirm Avascular Necrosis-Osteonecrosis

Radionuclide bone scan. This nuclear imaging technique uses a very small amount of radioactive material, which is injected into the blood to be detected by a scanner. This test shows blood flow to the bone and cell activity within the bone.

Overview

A bone scan is a nuclear imaging test that helps diagnose and track several types of bone disease. Your doctor may order a bone scan if you have unexplained skeletal pain, a bone infection or a bone injury that can’t be seen on a standard X-ray.

Why it’s done

Images of bone scans depicting hot spots

Hot spots

If you have unexplained bone pain, a bone scan might help determine the cause. The test is very sensitive to any difference in bone metabolism. The ability to scan the entire skeleton makes a bone scan very helpful in diagnosing a wide range of bone disorders, including:

Fractures

Arthritis

Paget’s disease of bone

Cancer originating in bone

Cancer that has metastasized to bone from a different site

Infection of the joints, joint replacements or bones (osteomyelitis)

Impaired blood supply to bones or death of bone tissue (avascular necrosis)

Another Day Another Victory

Awareness has been good many are responding making Avascular Necrosis Osteonecrosis Awareness Day one step closer to national awareness

Thanks to

Congressman Tim Ryan  Ohio who sent me this today

And thanks again to

Mayor Jamael Tito Brown – Youngstown Ohio

And

Senator Mike Rulli – Ohio

Who sent me awareness proclamations last week.

Its happening one state at a time.

I just heard from 10 states that they also will be supply this.

Life is always good but this week have been fantastic

Scroll on other posts to see other proclamations

 

 

Link to eBooklet   Avascular Necrosis Booklet by Deborah L. Andio

Thank You Proud Moment

Thank you to Youngstown Ohio Mayor Jamael Tito Brown and Senator Michael Rulli and Senate President Larry Obhof

What an honor

Help me raise awareness today and please like and share this post.

Thank You.

1st annual

#AvascularNecrosis #Osteonecrosis

#AwarenessDay #November29

AvascularNecrosis/Osteonecrosis Support Int’l

https://www.vindy.com/news/local-news/2019/11/city-state-recognize-poland-woman-with-rare-disease/